Shell crosslinked knedel-like nanoparticles for delivery of cisplatin: effects of crosslinking.
نویسندگان
چکیده
Polymeric micelles and shell crosslinked knedel-like (SCK) nanoparticles were loaded with up to 48% (w/w) cisplatin. These spherical cisplatin-loaded nanoparticles displayed sustained platinum release over 5 days in PBS, enhanced stability over free cisplatin in aqueous milieu, and significant antitumor activity in vitro against two cancer cell lines.
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ورودعنوان ژورنال:
- Nanoscale
دوره 5 8 شماره
صفحات -
تاریخ انتشار 2013